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Technology involving patent rights held by Keio University. For further information, please inquire at the KLL Desk.
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KIF研究プロジェクト
Research Project at Keio Innovation Foundry (KIF) as one of Keio University Faculty of Science and Technology 75th Anniversary Commemorative Project.

Group Exhibition Zone: Chemistry and Biology

Our lives are closely related to biomolecules, which not only make up our bodies, but also act as bioactive substances, some of which may be environmentally harmful, that are related to health, beauty and disease. This year’s group exhibition on chemistry and biology focuses on the themes of “substances” and “life”, and offers new insights into these topics to visitors. It involves 16 booths run by 15 members from the Department of Applied Chemistry, Department of Chemistry, and Department of Biosciences and Informatics. We will address a wide range of needs and interests!
BOOTH
01
Biomedical
Medical / Welfare
Analysis of glycan processing and elucidation of
action mechanism of bioactive compounds:
for development of disease therapeutic drugs
Research AssociateMIURA, Kazuki
Professor SIMIZU, Siro
Department of Applied Chemistry
In post-translational modifications of protein, glycosylation is closely related to various diseases. We are researching on relationship between glycosylation and disease using human cells and elucidation of action mechanism about biological activity natural compounds. In future, we think that these results can apply to various fields such as medicine.
BOOTH
02
Biomedical
Medical / Welfare
Development and application of
novel technology for the efficient synthesis of
highly-functional glycosides
Associate ProfessorTAKAHASHI, Daisuke
Professor TOSHIMA, Kazunobu
Department of Applied Chemistry
Various glycosides have been widely used as drugs, functional foods, surfactants, and cosmetic materials in our daily life. Therefore, creation of novel and highly-functional glycosides is attracted much attention. In this context, we focus on development of novel and efficient glycosylation technologies and creation of highly-functional glycosides.
BOOTH
03
Society & Environment
Society / Infrastructure
Development of new air purification technologies
to facilitate “subways with the world’s cleanest air”
Associate ProfessorOKUDA, Tomoaki
Department of Applied Chemistry
The subway system is an enclosed space and the attendant concerns about contaminated air, no systematic investigations on the air quality in subways have been carried out. This collaborative project aims to develop new technologies that will remove dust generated by subway by combining a know-how on electrostatic charging of brake dust with the filtration technologies.
BOOTH
04
Biomedical
Environment
CYCLEX project: New development of high-volume cyclone sampler for evaluating adverse health effect
caused by air particulate matter
Associate ProfessorOKUDA, Tomoaki
Department of Applied Chemistry
Recently, atmospheric aerosols such as PM2.5 are of serious concern for human health. Physical and chemical properties of aerosols are important as they provide metrics for their adverse health effects. Here I would like to introduce recent concept to elucidate these parameters using aerosol engineering techniques such as virtual impactor and cyclone system.
BOOTH
19
Biomedical
Medical / Welfare
Chemical Sensors and Biosensors
for Healthcare and Environmental Applications
ProfessorCITTERIO, Daniel
Assistant Professor HIRUTA, Yuki
Department of Applied Chemistry
Our laboratory works on the development of sensitive chemical sensors and biosensors for environmental and healthcare applications. Research topics include the development of functional fluorescent dyes, luminescent probes and functional nanomaterials for sensing applications. In addition, we make use of paper substrates to realize low-cost and simple (bio) chemical sensing devices.
BOOTH
20
Materials
Industry
Preparation of organic crystal exhibiting emission
and mechanical motion
Research Associate MIURA, Youhei
Department of Applied Chemistry
It was found that azaacene derivatives was prepared and it show aggregation induced emission that show fluorescence in aggregation state but not in solution. It was also found that crystal of the compound exhibit thermosalient effect that is crystal jumping by heating.
BOOTH
21
Materials
Other Areas
Control of Droplets for Continuous Processes
Assistant Professor FUJIOKA, Satoko
Department of Applied Chemistry
We have developed a novel static mixer which can make emulsions continuously. Because of its low energy consumption, no generation of heat and low risk of contamination, application for food industry is expected. We also investigate utilization of droplets as reaction fields for continuous production of fine particles.
BOOTH
22
Materials
Environment
Cell-sized droplet-type robots
exhibiting stimuli-responsibilities
Assistant ProfessorBANNO, Taisuke
Department of Applied Chemistry
Cell-sized self-assemblies composed of the designed and synthesized amphiphiles exhibit morphological changes and transition to other assemblies in response to external stimuli such as the temperature change and the addition of metal ions. These assemblies have potential applications as probes for exploring and collection of compounds in very small spaces.
BOOTH
23
Materials
Industry
Spontaneous generation of dynamisms
in chemical systems and cosmetic technologies
ProfessorASAKURA, Kouichi
Department of Applied Chemistry
One characteristic feature of living system is the spontaneous generation of dynamism. Artificial chemical systems, however, also can generate similar dynamism when they are in far-from-equilibrium conditions. Since cosmetics are frequently exposed to far-from-equilibrium conditions when they are used, controlling the dynamism generating in cosmetics might be an important technology.
BOOTH
24
Materials
Other Areas
Photoresponsive Nano-Magnets
Assistant ProfessorYAMAMOTO, Takashi
Professor EINAGA, Yasuaki
Department of Chemistry
A key issue in molecular electronics is the control of electronic states by optical stimuli. In this research, we would like to introduce photoresponsive nano-magnets such as nanoparticles and nanosheets.
BOOTH
31
Materials
Environment
Novel Organic-Inorganic Hybrid Materials
for Solar Energy Conversion and Optoelectronics
Associate Professor HASOBE, Taku
Assistant Professor SAKAI, Hayato
Department of Chemistry
In this presentation, we’d like to introduce our recent research results: organic-inorganic hybrid materials for solar energy conversion and optoelectronics.
BOOTH
32
Biomedical
Medical / Welfare
Discovery of the drug lead compounds
from marine organisms
Research AssociateIWASAKI, Arihiro
Professor SUENAGA, Kiyotake
Department of Chemistry
Some compounds produced by organisms exhibit useful biological activities, and their structures have been regarded as good motifs for the drug development. In order to discover novel drug lead compounds, we have investigated the secondary metabolites of marine organisms such as marine cyanobacteria.
BOOTH
33
Biomedical
Environment
Study in Nature! -Water bear and Planarian-
Associate Professor MATSUMOTO, Midori
Department of Biosciences and Informatics
We coexist with small organisms on the earth, which have amazing life force not found in humans. We are studying water bear that can survive in extreme conditions and planarian that can be regenerated even when cutting. Here, I would like to introduce their wonderful skill.
BOOTH
34
Biomedical
Medical / Welfare
Application of the designed protein nano-cage
Assistant Professor KAWAKAMI, Norifumi
Department of Biosciences and Informatics
We have recently produced 22 nm protein nano-cage that can incorporate small molecules, such as drug and pigment molecules, advantageous for the drug delivery system and the selective labeling of cells and molecules.
BOOTH
35
Biomedical
Medical / Welfare
Developmental Mechanism of Central Pattern Generator
Assistant ProfessorHOTTA, Kohji
Department of Biosciences and Informatics
I am now studying the developmental mechanism of central pattern generator which regulate locomotion.
BOOTH
36
Biomedical
Medical / Welfare
Biomaterials built from polymer materials
ProfessorFUJIMOTO, Keiji
Assistant Professor FUKUI, Yuuka
Department of Applied Chemistry
We focus on the design and synthesis of polymer materials (atto-reactor for nanocrystals and nano-fibers, core-shell particle for nano-imprinting), soft matters (liposome, gel particle) and bio-macromolecules (nanoparticle) possessing novel functionalities. Our research includes development of biomedical tools (nano-manipulating tool, nanocapsule) and techniques (cell-surface modification, particle scaffold for cell sheet) for drug delivery and tissue engineering.
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